With this review, the part of MCPs in modulating alphavirus-induced bone loss was investigated. We demonstrate that CHIKV an infection stimulates osteoclastogenesis, leading to important bone reduction. Recruitment of monocytic OC precursor cells on the ankle joint and tibial epiphysis was mediated in part by MCPs. Oral administration of Bindarit https://agathau974lkh2.loginblogin.com/profile