When symptomatic, PAD causes intermittent claudication, which happens to be pain during the legs that happens for the duration of going for walks and is relieved by relaxation; It's a manifestation of exercising-induced reversible ischemia, much like angina pectoris. 11,thirteen In contrast, CKD typically results in distal involvement in uremia https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/