In this article, we clearly show that conolidine, a all-natural analgesic alkaloid Utilized in conventional Chinese drugs, targets ACKR3, thereby delivering further evidence of a correlation between ACKR3 and discomfort modulation and opening substitute therapeutic avenues for the treatment method of Long-term discomfort. SubscribeSign up for our newslettersSee the https://matthewl147mjf5.wikigdia.com/user